Meet the provider: Jacob Rube, M.D.

Jacob Rube, M.D., Department of Neurology, originally worked part-time for Wayne Health from July 2019 to June 2020 while completing his fellowships. He became a full-time attending physician in July 2020. His areas of interest include diagnosis and treatment of both relapsing and progressive Multiple Sclerosis. He also specializes in other autoimmune neurological disorders such as NMOSD (Neuromyelitis Optica Spectrum Disorder), MOG antibody disease, Neurosarcoidosis, Myasthenia Gravis, Chronic inflammatory demyelinating polyneuropathy (CIDP), paraneoplastic disorders, and the neurologic complications of systemic autoimmune disorders such as Lupus and Sjogren’s Syndrome. He also injects Botox for migraine and spasticity.

Dr. Rube received his undergraduate degree from Touro College in Brooklyn, NY. He received his medical school training from Wayne State University and graduated in 2014. He interned for a year at State Island University Hospital, and completed his residency at Northwell Health in Manhasset, NY, where he was the chief resident. He completed a multiple sclerosis and neuroimmunology fellowship at WSU/DMC. Along with being a full-time attending physician, he is an assistant professor at WSU. Dr. Rube chose neurology because he enjoys that it’s like solving a puzzle. He also enjoys developing relationships with his patients and helping them solve their issues.

Dr. Rube enjoys working with the Metro Detroit community as there is so much need for quality neurological care, and the population is diverse. His patients have taught him that every individual on planet earth is unique, and their diseases are a unique experience for them. That a doctor needs to be sensitive to the way a patient lives there and tailor his recommendations for that individual. Dr. Rube believes that patients should be educated fully about their disease, there should be full transparency of all treatment options and that decision making should be a shared effort. In neuroimmunology and multiple sclerosis they have a plethora of treatment options and he believes in explaining all options to patients in a way that they can understand.

Dr. Rube feels blessed and privileged to be able to work every day and change people’s lives. He really enjoys his job. He strongly believes in, “If you enjoy your job, you will never work a day in your life”. Dr. Rube also works for the VA as a part-time physician and is the Wellness Director for the Wayne State Neurology residency program. He participates in clinical trials for multiple sclerosis, myasthenia gravis and CIDP.

In his free time, Dr. Rube does daily stretching and exercise, volunteers for his synagogue and spends time with his wife and children.

To request an appointment with Dr. Rube, visit our appointments page.